Red Raspberry and Soy Isoflavone exert estrogenic effects to reduce hot flashes. Red Clover activates opioid system receptors which regulate temperature, mood, and hormonal levels. Wild Yam helps boost estrogen levels. Licorice exerts both anti-estrogenic and estrogenic action to help regulate estrogen levels. Ginger helps alleviate hot flashes and night sweats. 5-HTP increases the product of serotonin levels In the brain to improve mood, sleep, and temperature control.